Ever since the Food and Drug Administration (FDA) authorized emergency use of the vaccines from Pfizer-BioNTech and Moderna, older adults and their caregivers have worried about the shot’s safety. People want to be certain that the new COVID-19 vaccines are safe for the elderly. Also of concern is the possibility of any long-term vaccine side effects. Is it better to wait and see how the vaccines affect people before signing up to get vaccinated?

These are a few of the concerns and questions caregivers and older adults may share. However, medical experts say the vaccines have proven to be very safe. And to make that point, several well-known Americans like Mike Pence (61), Anthony Fauci (80), and Joe Biden (78), to name just a few, have publicly rolled up their sleeves for their first dose of the vaccine demonstrating confidence in the vaccine to safely protect them from becoming infected by the coronavirus.

Studies Show COVID-19 Vaccine Side Effects Are Generally Mild

The main worry about the COVID-19 vaccine being safe for the elderly is side effects. Yet these have proven to be minimal. “The side effects have been mild to moderate and include arm soreness, fatigue, headache,” says Judith Beizer, a geriatric pharmacist and clinical professor at St. John’s University College of Pharmacy and Health Sciences in Queens, New York. In fact, a study published by the New England Journal of Medicine shows older adults reported fewer side effects after receiving the COVID-19 vaccine than younger people.

“Generally, side effects occur at the time you receive a vaccine,” Beizer explains. The Pfizer-BioNTech vaccine is administered in two doses three weeks apart. The Moderna vaccine, which is the vaccine scheduled to be given to residents and staff at The Classic, is administered in two doses four weeks apart. Getting two doses ensures the strongest immunity to the coronavirus. “With these vaccines, side effects occur after receiving the second dose,” Beizer says. “That’s why doctors tell people to plan for a lighter schedule on the day of the second dose or the day after the dose. It’s the same with shingles vaccine sometimes there are side effects with the second dose.”

People who have had a severe allergic reaction (called anaphylaxis) to any of the vaccines’ ingredients in the past shouldn’t get the COVID-19 vaccine, according to the Centers for Disease Control and Prevention (CDC). Doctors, nurses, medical assistants, and anyone who administers the vaccine is required to keep antidote medication close by in the event a serious reaction occurs.

The “Wait and See” Vaccine Approach

Some caregivers and their families also worry that not enough time was taken to study the new COVID-19 vaccines and have decided to take a wait-and-see approach before getting vaccinated. Unfortunately, the risks of contracting the coronavirus for older adults can be deadly. “While a lot of people are waiting for the trials to be continued over a longer period of time, it really isn’t necessary,” says Beizer.

There are good reasons to be confident about the vaccine safety. A large number of people were included in the coronavirus vaccine studies called trials and many participants were older adults. The Moderna trials involved about 30,000 people, of which 7,000 are age 65 or older. The Pfizer trials involved 44,000 people, and nearly 7,500 of them are 65 or older. Reactions to the vaccines were monitored closely for more than two months and continue to be monitored which is why the absence of serious side effects has been such exciting news.

Scientists who are not associated with the drug companies have checked the studies too. Results from the trials were carefully reviewed by the FDA and medical advisory boards to make sure they were correct. The Advisory Committee on Immunization Practices at the CDC also reviewed all the safety information before recommending the COVID-19 vaccines. These experts determined the COVID-19 vaccines are safe and effective. The Moderna and Pfizer-BioNTech vaccines have been shown to be more than 94% effective in protecting people from becoming infected by the coronavirus, and countries all around the world are beginning vaccine programs for their elderly and health care workers. Both vaccines use the synthetic mRNA (a single-stranded RNA molecule that is complementary to one of the DNA strands of a gene) which triggers our bodies’ immune response to fight the protein found on the spikes of the virus.

Vaccine Safety for Older Adults with Health Conditions

Is the COVID-19 vaccine safe for elderly people who have other health conditions such as heart disease, asthma, or diabetes? So far, people with preexisting conditions have not experienced different or more severe reactions to the vaccine compared with people without other medical conditions.

“Nothing in the research shows that older adults who are weak are more susceptible to vaccine side effects than others,” says Beizer. “But as time goes on, and more and more people receive the vaccine, more information will become available and older adults are the people we want to be protecting.”

Before receiving the COVID-19 vaccine, you or your older relative must tell the person giving the vaccine if you have any allergies, a fever, or bleeding disorders. The health care professional administering the vaccine should know if anyone has a compromised immune system, is receiving immunosuppressive therapy, or has already received another COVID-19 shot.


  • Centers for Disease Control and Prevention: Interim Considerations. “Preparing for the Potential Management of Anaphylaxis at COVID-19 Vaccination
  • Moderna – “Moderna Announces FDA Authorization of Moderna COVID-19 Vaccine in U.S.”
  • Pfizer – “Pfizer and BioNTech Receive FDA Advisory Committee Vote Supporting Potential First Emergency Use Authorization for Vaccine to Combat COVID-19 in the U.S.”
  • Centers for Disease Control and Prevention – “How CDC is Making COVID-19 Vaccine Recommendations”